Detall de la convocatòria

Expressió d'interès - Expression of interest

Característiques

Característica
Objectiu de la convocatòria
The Mark Foundation for Cancer Research is dedicated to accelerating exciting academic discoveries into new therapies and platforms that will substantially improve outcomes for cancer patients. Currently, there are few options for academic scientists to obtain the resources and know-how to advance drug discovery efforts for promising new cancer targets.
Característiques principals
Eligible therapeutic modalities:
  • Large molecules / biologics
  • Small molecules (including heterobifunctionals)
  • Peptides
  • Conjugates (ADC, radioconjugates)
  • Nucleic acids (ASO, RNA)
    Eligible project stages:
  • Lead discovery – generate and credential new leads against a validated target
  • Optimization – assess and enhance efficacy, safety, and DMPK of existing leads
    The following project topics are ineligible for this award:
  • Drug delivery technologies or optimizations
  • Drug repurposing
  • Preclinical development (IND-enabling studies)
  • Cell therapies, gene therapies, viral therapies, and vaccines
    • Convocatòria (URL)
    https://themarkfoundation.org/drug-discovery-award-3/
    Requisits
  • Principal investigators must hold an MD, PhD, or equivalent and be independent researchers at their respective institutions.
  • Individuals are limited to one application as principal investigator but may be co-investigators on other proposals without limitation.
    • Dotació
    Up to $1.000.000
    Durada
    12-36 months
    Documentació
    The Project Concept Letter can be a maximum of 2 pages, including any figures or tables. References may be included on an additional page. The Project Concept Letter must be submitted as a PDF file and contain the following information with headings:
  • Project title
  • Target description and validation summary
  • Lead identification summary (for Lead Optimization projects only)
  • Brief description of competitive landscape
  • Synopsis of research plan
  • Problem statement describing unmet clinical need for cancer patients and impact opportunity
    Full applications will be accepted by invitation only, after review of Project Concept Letters. Additional guidelines will be provided to invited applicants. Revenue-sharing terms will apply. Details will be shared upon approval of the project for funding.

    • Arxius

    Arxiu
    Drug Discovery Award _ The Mark Foundation for Cancer Research.pdf