Detall de la convocatòria

Expressió d'interès - Expression of interest

Característiques

Característica
Objectiu de la convocatòria
This grant mechanism will focus on the science behind HER2 alterations as oncogenic drivers of malignancy and/or the development of novel therapeutic approaches for patients with tumors harboring HER2 mutations and/or other HER2 alterations.
Característiques principals
We encourage applications on a wide variety of topics related to HER2 alterations and lung cancer, including but not limited to the following:
  • The proposal must be associated with a clinical trial, either ongoing or planned as a result of the project. The trial can investigate novel treatment approaches, new therapies (i.e. next generation drugs or agents with novel mechanisms of action), and novel combinations. Therapy can include targeted agents (TKIs), antibody-drug conjugates, immunotherapies, cell therapies etc. if there is a reasonably strong rationale supporting the investigation.
  • The proposal must have a program of basic and/or translational work associated with the clinical trial. Topics of interest can include but are not limited to mechanisms of primary or secondary resistance, studies on the immune landscape and tumor microenvironment, biology and mechanisms of tumor progression, identification of biomarkers to predict sensitivity to specific therapies, methods for optimizing treatment (efficacy and/or tolerability), etc.
  • The proposal must include studies in patients with lung cancer harboring HER2-mutations and /or other HER2 alterations.
  • A patient/patient advocate needs to be part of the research team applying for the grant and that this individual should have a role in the design of the research.
    • Lloc de presentació
    El personal de l'HMRIB i PSMAR que necessiteu més informació adreceu-vos a:
    Research Grants and Contracts Office. C/ Doctor Aiguader, 88. 08003-Barcelona. Tel.: 93.316.04.00.
    Carol Barnwell: cbarnwell@researchmar.net Ext.: 1670
    Marta López: mlopez4@researchmar.net Ext.: 1576
    Convocatòria (URL)
    https://www.lungcancerresearchfoundation.org/research/funding-opportunities-2025/?utm_source=Lung%20Cancer%20Research%20Foundation&utm_campaign=41a8097d0b-EMAIL_CAMPAIGN_2025_01_06_06_53&utm_medium=email&utm_term=0_-41a8097d0b-8340196
    Requisits
    Investigators must be affiliated with a non-profit, academic or research institution. An applicant must have a postdoctoral or clinical research fellow appointment and/or a faculty position and may have any level of research experience. Applicants from US-based and international institutions are eligible to apply and may hold any residency/citizenship status. Applicants are prohibited from applying in more than one of LCRF’s funding tracks in the same cycle. Any questions regarding eligibility should be directed to the LCRF Grants Office before the submission of an application.
    Dotació
    $500,000
    Durada
    2 years
    Documentació
    https://proposalcentral.com/GrantOpportunities.asp?GMID=247

    Arxius

    Arxiu
    2025-LCRF-HER2-RFP.pdf