Detall de la convocatòria

Característiques

Característica
Objectiu de la convocatòria
This program aims to advance the understanding of Frontotemporal Degeneration (FTD), its disease mechanisms, and validated biomarkers with a clear context-of-use by supporting the development of drugs or devices.
Característiques principals
Proposals should include clinical trial readiness activities and early/mid-stage (phase 0–2) clinical trials with defined go/no-go criteria. Both novel and repurposed drugs and devices, as well as disease-modifying and symptomatic approaches, are eligible. Clinical trials should incorporate:
  • Biological mechanisms with a sound scientific rationale for FTD.
  • Biomarkers that allow evaluation of target engagement, downstream pharmacologic and biological effects.
  • Trial designs aligned with constraints associated with a rare disease population.
  • Clinical outcome measures that provide insight into drug mechanisms and disease progression.
  • Therapeutics applicable to sporadic or genetic forms of FTD, with particular encouragement for trials targeting sporadic FTD.
    • Lloc de presentació
    HMRIB and PSMAR staff who need more information should contact:
    Research Grants and Contracts Office. C/ Doctor Aiguader, 88. 08003 Barcelona. Tel.: 93.316.04.00.
    Carol Barnwell: [email protected] Ext.: 1670
    Marta López: [email protected] Ext.: 1576
    Júlia Vidal: [email protected] Ext.: 1736
    Convocatòria (URL)
    https://www.alzdiscovery.org/research-and-grants/funding-opportunities/the-treat-ftd-fund
    Informació addicional
    This call follows a two-step procedure. Applicants should first submit a Letter of Intent (LOI) through the ADDF Funding Portal.
    Requisits
    Open to researchers and clinicians worldwide at:
  • Academic medical centers, universities, or non-profits. Industry partnerships are encouraged.
  • Biotechnology companies. Existing companies and new startups are both eligible.
    • Dotació
    $2,500,000
    Durada
    1 to 3 years

    Arxius

    Arxiu
    ADDF The Treat FTD Fund.pdf
    ADDF The Treat FTD Fund_Application Instructions.pdf