Detall de la convocatòria

Característiques

Característica
Objectiu de la convocatòria
The Alzheimer's Drug Discovery Foundation (ADDF) funds drug discovery and development research programs in the field of Alzheimer's disease (AD), related dementias and cognitive aging. The ADDF seeks to fill the critical translational funding gap between basic research and later stage drug development by funding promising drug discovery and development programs. In addition to funding academic programs, the ADDF also invests in and creates early stage biotechnology companies. The ADDF also co-sponsors conferences to stimulate new ideas and approaches in areas of interest to the Foundation.
Característiques principals
Research investigating the pathologic mechanisms underlying frontotemporal degeneration (FTD) is advancing, creating new targets for drug discovery. As potential therapies move forward, the need for biomarkers for early diagnosis, to distinguish FTD subtypes, and to monitor disease progression is also critical. The Alzheimer’s Drug Discovery Foundation (ADDF) and The Association for Frontotemporal Degeneration (AFTD) seek to accelerate and support innovative drug discovery programs and biomarker development for FTD through this Request for Proposals (RFP).

Priority areas for this program include:
  • Development and testing of novel high throughput screening assays
  • Preclinical testing of novel or repurposed drug candidates
  • Proteomics/transcriptomics/metabolomics for FTD biomarkers
  • Development/validation of CSF biomarker assays to distinguish TDP-43 or tau-based FTD
  • Functional imaging methods that correlate to FTD disease symptoms
  • Neurodegeneration and differential connectivity patterns (white and grey matter) in FTD disorders
  • Innovate software, algorithm-based approaches to improve quantitative image analysis for FTD
  • Innovative pilot clinical trials
    • Lloc de presentació
    El personal de l'IMIM i PSMAR que necessiteu més informació adreceu-vos a:
    Servei de Recerca. C/ Doctor Aiguader, 88. 08003-Barcelona. Tel.: 93.316.05.76.
    Marta López: mlopez4@imim.es Ext.: 1576
    Carol Barnwell: cbarnwell@imim.es Ext.: 1670
    Convocatòria (URL)
    http://www.alzdiscovery.org/research-and-grants/request-for-proposal
    Dotació
    150,000-$200,000
    Durada
    1 year.
    Applications with extended timelines or larger budgets may be considered on a per project basis.
    AVÍS IMPORTANT
    The deadline date for applications is September 22nd, 2015. Submission of a Letter of Intent (LOI) is required prior to September 8th, 2015. LOIs are reviewed on a rolling basis and can be submitted any time prior to the date above.

    Arxius

    Arxiu
    Request for Proposals